Dynamics of Inflammatory Parameters after Endovascular and Open Infrarenal Abdominal Aneurysm Repair

Abstract

Background: The aim of this study was to investigate the dynamics of inflammatory parameters in patients after infrarenal abdominal aneurysm surgery.

Methods: The retrospective study included patients with operated infrarenal abdominal aneurysm, divided into two groups: (i) patients receiving endovascular aneurysm repair (EVAR); (ii) patients that had open surgery. General data and inflammatory parameters (CRP, leukocytes, platelets and fibrinogen) were taken during hospitalization, compared mutually and analyzed.

Main findings: All inflammatory parameters, observed preoperatively, were close to the referent range. Serum CRP values leukocyte counts in EVAR patients raised after operation, but returned to the reference range more quickly. Around the middle of their hospital stay and at day of discharge, the open surgery group had statistically significantly higher platelet values than the EVAR group. During the preoperative period and in the middle of hospitalization, the open surgery group showed higher fibrinogen values, while at day of discharge, the EVAR group showed statistically significantly higher fibrinogen values.

Principal conclusions: Observed serum inflammatory parameters (CRP, leukocytes, fibrinogen and platelets) in different phases of hospitalization were lower and closer to the reference value in patients with infrarenal abdominal aneurysm who received EVAR compared to patients receiving open surgery. All observed parameters other than fibrinogen returned to the reference value faster in EVAR patients.